UK Biobank

Large-scale biomedical database and research resource

Logo of UK Biobank

UK Biobank facility in Stockport

UK Biobank is a large-scale biomedical database and research resource, containing in-depth genetic and health information from half a million UK participants. It is a major international health resource and aims to improve the prevention, diagnosis, and treatment of a wide range of serious and life-threatening illnesses, including cancer, heart diseases, stroke, diabetes, arthritis, osteoporosis, eye disorders, depression, and forms of dementia.

History

The concept of UK Biobank was first proposed in the late 1990s, with the aim of creating a large-scale resource for studying the role of genetic and environmental factors in disease. The project was officially launched in 2006, with the recruitment of participants beginning in 2007. By 2010, UK Biobank had successfully recruited 500,000 participants aged between 40 and 69 years.

Data Collection

UK Biobank collects a wide range of data from its participants, including physical measurements, lifestyle information, and biological samples. Participants undergo a baseline assessment, which includes measurements such as height, weight, blood pressure, and bone density. They also provide blood, urine, and saliva samples for future analysis. In addition, participants complete detailed questionnaires about their lifestyle, diet, and medical history.

Research and Impact

The data collected by UK Biobank is made available to researchers worldwide, and it has been used in numerous studies to advance understanding of various diseases. The resource has contributed to significant discoveries in genetics, epidemiology, and public health. UK Biobank's open-access model encourages collaboration and innovation in biomedical research.

Ethical Considerations

UK Biobank operates under strict ethical guidelines to ensure the privacy and confidentiality of its participants. All data is anonymized, and participants have the right to withdraw from the study at any time. The project is overseen by an independent Ethics and Governance Council, which ensures that the research conducted is in the public interest and respects participants' rights.

Funding

UK Biobank is funded by a combination of government and charitable sources, including the Medical Research Council, the Wellcome Trust, the Department of Health and Social Care, and the Scottish Government.

Related pages

• Biobank
• Genetic epidemiology
• Public health

References

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  Logo of UK Biobank

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  Biobank Stockport, 1st October 2022

UK_Biobank

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  UK Biobank Logo

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  Biobank Stockport, 1 Oct 2022