Ultrase

From WikiMD's Wellness Encyclopedia

Ultrase is a brand name for a type of enzyme supplement used primarily in the treatment of pancreatic enzyme insufficiency (PEI). PEI is a condition characterized by the insufficient production of digestive enzymes by the pancreas, leading to difficulties in digesting food properly. This condition is often associated with chronic pancreatitis, cystic fibrosis, and other diseases that affect the pancreas. Ultrase is part of a class of medication known as pancreatic enzyme products (PEPs), which are designed to supplement the body's natural digestive enzymes, thereby improving nutrient absorption and reducing gastrointestinal symptoms such as diarrhea, fat in the stools (steatorrhea), and weight loss.

Composition and Mechanism[edit | edit source]

Ultrase contains a mixture of digestive enzymes, including lipases, proteases, and amylases. These enzymes are derived from porcine (pig) pancreas glands and are similar to the enzymes naturally produced by the human pancreas. The lipases help break down fats, proteases aid in the digestion of proteins, and amylases assist in the digestion of carbohydrates.

The mechanism of action of Ultrase involves the replacement of these digestive enzymes that the pancreas is unable to produce in sufficient quantities. By taking Ultrase with meals and snacks, patients with PEI can improve their digestion and absorption of nutrients, which helps in managing the symptoms and nutritional deficiencies associated with the condition.

Dosage and Administration[edit | edit source]

The dosage of Ultrase is individualized based on the patient's weight, condition, and the severity of enzyme insufficiency. It is crucial for patients to follow their healthcare provider's instructions regarding the dosage and timing of the enzyme supplements. Typically, the capsules are taken with every meal and snack, with the amount adjusted according to the fat content of the food and the patient's response to treatment.

Side Effects and Precautions[edit | edit source]

While Ultrase is beneficial for many patients with PEI, it can cause side effects in some individuals. Common side effects include gastrointestinal symptoms such as nausea, abdominal cramps, and diarrhea. Rarely, patients may experience allergic reactions to the porcine-derived enzymes.

Patients with known allergies to pork products should avoid using Ultrase. Additionally, because the enzymes can irritate the oral mucosa, the capsules should be swallowed whole and not chewed.

Conclusion[edit | edit source]

Ultrase represents a critical treatment option for individuals with pancreatic enzyme insufficiency, offering the possibility of improved digestion and nutrient absorption. As with any medication, it is important for patients to work closely with their healthcare provider to determine the most appropriate treatment plan for their specific needs.


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Contributors: Prab R. Tumpati, MD