Umbilical cord ulcer with intestinal atresia
=Umbilical Cord Ulcer with Intestinal Atresia =
Umbilical cord ulcer with intestinal atresia is a rare congenital condition characterized by the presence of an ulceration on the umbilical cord and an associated intestinal atresia, which is a blockage or absence of a portion of the intestine. This condition is of significant clinical interest due to its implications for neonatal health and the challenges it presents in prenatal diagnosis and postnatal management.
Clinical Presentation[edit | edit source]
The clinical presentation of umbilical cord ulcer with intestinal atresia can vary, but typically includes signs of intestinal obstruction in the newborn. These signs may include:
- Abdominal distension
- Bilious vomiting
- Failure to pass meconium
The presence of an umbilical cord ulcer may be noted at birth, although it is not always immediately apparent.
Pathophysiology[edit | edit source]
The exact pathophysiology of umbilical cord ulcer with intestinal atresia is not fully understood. However, it is believed that the ulceration of the umbilical cord may be related to vascular compromise or an inflammatory process that also affects the developing intestine, leading to atresia. Further research is needed to elucidate the mechanisms involved.
Diagnosis[edit | edit source]
Diagnosis of this condition is often made postnatally, although prenatal ultrasound may reveal signs suggestive of intestinal atresia, such as polyhydramnios or dilated bowel loops. The umbilical cord ulcer may be identified upon physical examination after birth.
Treatment[edit | edit source]
The primary treatment for intestinal atresia is surgical intervention to remove the atretic segment and restore intestinal continuity. The management of the umbilical cord ulcer involves careful monitoring and supportive care to prevent infection and promote healing.
Prognosis[edit | edit source]
The prognosis for infants with umbilical cord ulcer and intestinal atresia depends on the severity of the atresia and the presence of any associated anomalies. With prompt surgical treatment and appropriate neonatal care, many infants can recover and lead healthy lives.
See Also[edit | edit source]
External Links[edit | edit source]
- [Rare Diseases Information Center](https://rarediseases.info.nih.gov/)
NIH genetic and rare disease info[edit source]
Umbilical cord ulcer with intestinal atresia is a rare disease.
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Contributors: Prab R. Tumpati, MD
