VU-0238429

VU-0238429 is a chemical compound that is known for its role as a M1 muscarinic acetylcholine receptor positive allosteric modulator. This compound is often used in pharmacology and neuroscience research.

Chemistry

VU-0238429 is a synthetic compound. It is classified as a positive allosteric modulator, which means it enhances the activity of the neurotransmitter acetylcholine at the M1 muscarinic acetylcholine receptor.

Pharmacology

In pharmacology, VU-0238429 is used to study the M1 muscarinic acetylcholine receptor. This receptor is one of five muscarinic acetylcholine receptors (M1-M5) that are found in the central nervous system and peripheral tissues. The M1 receptor is predominantly found in the brain and is involved in cognitive functions such as learning and memory.

Neuroscience

In neuroscience research, VU-0238429 is used to investigate the role of the M1 receptor in various neurological and psychiatric disorders. These include Alzheimer's disease, schizophrenia, and Parkinson's disease. The compound's ability to enhance the activity of the M1 receptor makes it a valuable tool in studying these conditions.

Research Applications

VU-0238429 has been used in various research studies. For example, it has been used to investigate the potential therapeutic effects of enhancing M1 receptor activity in models of Alzheimer's disease and schizophrenia. It has also been used to study the role of the M1 receptor in the regulation of sleep and wakefulness.

See Also

• Muscarinic acetylcholine receptor
• Positive allosteric modulator
• Neurotransmitter
• Alzheimer's disease
• Schizophrenia
• Parkinson's disease