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VEXAS Syndrome is a rare, recently discovered inflammatory condition that primarily affects men over the age of 50. The syndrome is characterized by symptoms such as fevers, skin rashes, and various forms of inflammation affecting multiple parts of the body.

Symptoms[edit | edit source]

The symptoms of VEXAS Syndrome can vary widely among individuals. Common symptoms include:

Fever
Skin rash
Inflammation affecting multiple parts of the body
Blood clots
Anemia
Fatigue

Causes[edit | edit source]

VEXAS Syndrome is caused by mutations in the UBA1 gene. This gene provides instructions for making a protein that is involved in the process of removing and recycling damaged or unneeded proteins within cells.

Diagnosis[edit | edit source]

Diagnosis of VEXAS Syndrome is typically made through genetic testing, which can identify the presence of the UBA1 gene mutation.

Treatment[edit | edit source]

There is currently no cure for VEXAS Syndrome. Treatment is focused on managing symptoms and preventing complications. This may include medications to reduce inflammation and prevent blood clots.

Prognosis[edit | edit source]

The prognosis for individuals with VEXAS Syndrome can vary. Some individuals may experience severe symptoms and complications, while others may have a milder disease course.

References[edit | edit source]

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