Virodhamine

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Virodhamine is a cannabinoid that was discovered in June 2002. It is named after the Sanskrit word 'virodha', which means opposition or antagonism. This is due to its peculiar behavior as a partial agonist and antagonist at the CB1 receptor and CB2 receptor respectively.

Discovery[edit | edit source]

Virodhamine was discovered by a team of researchers at the Medical College of Virginia. The team was led by Dr. Aron Lichtman, a professor of Pharmacology and Toxicology. The discovery was published in the journal Nature in June 2002.

Structure and Function[edit | edit source]

Virodhamine is structurally similar to anandamide, another endocannabinoid. However, it differs in the position of its ester linkage. Virodhamine is a partial agonist at the CB1 receptor and an antagonist at the CB2 receptor. This means it can both activate and inhibit these receptors, depending on the circumstances.

Biological Effects[edit | edit source]

The biological effects of virodhamine are still not fully understood. However, it is known to have anti-inflammatory and analgesic properties. It is also thought to play a role in the regulation of mood and appetite.

Research[edit | edit source]

Research into virodhamine is ongoing. It is hoped that a better understanding of this compound could lead to new treatments for a range of conditions, including chronic pain, inflammation, and mood disorders.

See Also[edit | edit source]

Virodhamine Resources
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Contributors: Prab R. Tumpati, MD