Vitamin K1
Vitamin K1 also known as Phylloquinone is a type of Vitamin K that is naturally present in certain foods and can also be taken as a dietary supplement. It is a fat-soluble vitamin that plays an essential role in blood clotting and bone metabolism.
Sources of Vitamin K1[edit | edit source]
Vitamin K1 is found in green leafy vegetables such as spinach, kale, and broccoli. It can also be found in certain vegetable oils like soybean oil and canola oil. The human body is able to store small amounts of Vitamin K1 in the liver for future use.
Function of Vitamin K1[edit | edit source]
Vitamin K1 is essential for the functioning of several proteins involved in blood clotting, bone metabolism, and the regulation of blood calcium levels. It acts as a coenzyme for the enzyme gamma-glutamyl carboxylase, which catalyzes the carboxylation of the amino acid glutamic acid, a critical step in the formation of blood clotting proteins.
Deficiency of Vitamin K1[edit | edit source]
Vitamin K deficiency can lead to excessive bleeding, which can be life-threatening. Symptoms of deficiency include easy bruising, bleeding gums, and blood in the urine or stool. People at risk for deficiency include those with malabsorption disorders, such as celiac disease or Crohn's disease, and those who are on long-term antibiotic therapy.
Vitamin K1 Supplements[edit | edit source]
Vitamin K1 supplements are available over the counter in many health food stores and pharmacies. They are often recommended for people who are at risk of deficiency, such as those with certain digestive disorders or people who are taking blood thinners.
Safety and Side Effects[edit | edit source]
Vitamin K1 is generally considered safe when consumed in food or taken as a supplement in the recommended doses. However, high doses can cause side effects such as flushing, sweating, and changes in liver function tests. People on blood thinners should not take Vitamin K1 supplements without first consulting their healthcare provider.
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Contributors: Prab R. Tumpati, MD