X-linked dominant inheritance

X-linked dominant

• X-linked dominant inheritance refers to genetic conditions associated with mutations in genes on the X chromosome.
• In females (who have two X chromosomes), a mutation in one of the two copies of the gene in each cell is sufficient to cause the disorder.
• In males (who have only one X chromosome), a mutation in the only copy of the gene in each cell causes the disorder.
• In most cases, males experience more severe symptoms of the disorder than females.
• A characteristic of X-linked inheritance is that fathers cannot pass X-linked traits to their sons (no male-to-male transmission).

See also

• Sex linkage
• X-linked recessive inheritance

X-linked dominant inheritance Resources
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