Yessotoxin
Yessotoxin (YTX) is a polyether toxin produced by certain species of marine dinoflagellates, primarily those belonging to the genus Lingulodinium and Protoceratium. It was first isolated from the digestive glands of scallops in Japan and has since been identified in various marine organisms worldwide.
Structure and Properties[edit | edit source]
Yessotoxin is a large polyether compound with a complex structure characterized by multiple ether rings. Its molecular formula is C55H82O21. The toxin is known for its stability, being resistant to heat and acidic conditions, which makes it a persistent contaminant in marine environments.
Production and Sources[edit | edit source]
Yessotoxin is produced by dinoflagellates such as Lingulodinium polyedra and Protoceratium reticulatum. These microorganisms can proliferate in marine environments, leading to harmful algal blooms (HABs). The toxin accumulates in filter-feeding shellfish, which can then pose a risk to human health if consumed.
Toxicity and Health Effects[edit | edit source]
Yessotoxin is known to affect the cardiovascular and immune systems. It has been shown to induce apoptosis (programmed cell death) in various cell types. Despite its toxicity, YTX is not classified as a diarrhetic shellfish poison (DSP) because it does not cause diarrhea in humans. However, it is still considered a significant marine biotoxin due to its potential health impacts.
Detection and Regulation[edit | edit source]
Detection of yessotoxin in seafood is typically performed using methods such as liquid chromatography coupled with mass spectrometry (LC-MS). Regulatory limits for YTX in shellfish have been established in various countries to ensure food safety. For instance, the European Union has set a maximum permissible level of 3.75 mg YTX equivalents per kg of shellfish meat.
Research and Applications[edit | edit source]
Research on yessotoxin is ongoing to better understand its mechanisms of action and potential uses. Some studies have explored its application in cancer research due to its ability to induce apoptosis in cancer cells. However, more research is needed to fully elucidate its potential therapeutic benefits and risks.
Related Pages[edit | edit source]
Categories[edit | edit source]
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
WikiMD's Wellness Encyclopedia |
Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
WikiMD is not a substitute for professional medical advice. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD