Young's syndrome

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Young's syndrome
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Young's syndrome, also known as azoospermia sinopulmonary infections, sinusitis-infertility syndrome and Barry-Perkins-Young syndrome, is a rare condition that encompasses a combination of syndromes such as bronchiectasis, rhinosinusitis and reduced male fertility.[1][2][3] In individuals with this syndrome the functioning of the lungs is usually normal but the mucus is abnormally viscous. The reduced fertility ([obstructive [azoospermia]]) is due to functional obstruction of sperm transport down the genital tract at the epididymis, where the sperm is found in viscous, lipid-rich fluid.[3][4] The syndrome was named after Donald Young,[5] the urologist who first made observations of the clinical signs of the syndrome in 1972.[6]

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References[edit | edit source]

  1. , Young's syndrome. Obstructive azoospermia and chronic sinopulmonary infections, N. Engl. J. Med., Vol. 310(Issue: 1), pp. 3–9, DOI: 10.1056/NEJM198401053100102, PMID: 6689737,
  2. Young syndrome at NIH's Office of Rare Diseases
  3. 3.0 3.1 Young's syndrome - General Practice Notebook
  4. Definition: Young syndrome from Online Medical Dictionary
  5. , Obituary of Donald Herron Young, BMJ, Vol. 326(Issue: 7382), pp. 226, DOI: 10.1136/bmj.326.7382.226/g, PMC: 1125087, Full text,
  6. Online Mendelian Inheritance in Man (OMIM) Young syndrome -279000


  • ,
 Young's syndrome. An association between male sterility and bronchiectasis, 
 West. J. Med., 
 
 Vol. 144(Issue: 6),
 pp. 744–6,
 
 PMID: 3727536,
 PMC: 1306774,

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