ZNF268

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Protein ZNF268 PDB 2EL4

ZNF268

ZNF268 is a protein-coding gene located on chromosome 12 in humans. It plays a crucial role in the regulation of gene expression and is involved in various cellular processes. The protein encoded by ZNF268 contains zinc finger domains, which are known for their ability to bind to specific DNA sequences and regulate gene transcription.

Function[edit | edit source]

ZNF268 functions as a transcription factor, meaning it can bind to specific DNA sequences and control the expression of target genes. It is involved in the regulation of cell growth, differentiation, and development. Studies have shown that ZNF268 plays a role in various biological processes, including embryonic development and immune response.

Structure[edit | edit source]

The ZNF268 gene encodes a protein that contains multiple zinc finger domains. These domains are responsible for the DNA-binding activity of the protein. The specific arrangement of zinc fingers in ZNF268 allows it to recognize and bind to specific DNA sequences, thereby regulating the expression of target genes.

Role in Disease[edit | edit source]

Mutations in the ZNF268 gene have been associated with certain diseases and disorders. For example, dysregulation of ZNF268 expression has been linked to cancer development and progression. Further research is needed to fully understand the implications of ZNF268 mutations in disease states.

Interactions[edit | edit source]

ZNF268 has been shown to interact with various other proteins and transcription factors in the cell. These interactions are important for the proper functioning of ZNF268 in gene regulation and cellular processes. Understanding the protein-protein interactions of ZNF268 can provide insights into its biological functions.

References[edit | edit source]

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Contributors: Prab R. Tumpati, MD