Ze339

Herbal extract used for treating allergic rhinitis

Ze339 is a standardized extract derived from the leaves of the butterbur plant, Petasites hybridus. It is primarily used for the treatment of allergic rhinitis, commonly known as hay fever. Ze339 is known for its anti-inflammatory properties and is considered an alternative to conventional antihistamines.

Composition and Extraction

Ze339 is extracted from the leaves of the butterbur plant, which is native to Europe and parts of Asia. The extraction process involves removing potentially harmful pyrrolizidine alkaloids (PAs) to ensure the safety of the extract for human consumption. The active components of Ze339 are believed to be sesquiterpenes, which contribute to its anti-inflammatory effects.

Butterbur plants prepared for planting

Mechanism of Action

Ze339 works by inhibiting the release of leukotrienes and histamines, which are chemicals in the body that contribute to allergic reactions. By blocking these substances, Ze339 helps reduce symptoms such as nasal congestion, sneezing, and itchy eyes. The extract's anti-inflammatory properties also help in reducing the swelling of nasal passages.

Clinical Use

Ze339 is used as a natural remedy for managing symptoms of allergic rhinitis. It is often preferred by individuals seeking alternatives to synthetic antihistamines, which can cause side effects such as drowsiness. Clinical studies have shown that Ze339 is effective in reducing the symptoms of hay fever, making it a viable option for those with mild to moderate allergies.

Safety and Side Effects

The safety of Ze339 is enhanced by the removal of pyrrolizidine alkaloids during the extraction process. This makes it safe for long-term use in managing allergic symptoms. Common side effects are minimal and may include mild gastrointestinal discomfort. However, individuals with known allergies to plants in the Asteraceae family should exercise caution.

Butterbur growing on a Swiss farm

Regulatory Status

Ze339 is available as an over-the-counter supplement in many countries. It is marketed under various brand names and is subject to regulations governing herbal supplements. In some regions, it is classified as a traditional herbal medicinal product.

Related Pages

• Allergic rhinitis
• Butterbur
• Antihistamine
• Herbal medicine