Zoster vaccine recombinant, adjuvanted
Zoster vaccine recombinant, adjuvanted - A recombinant, subunit herpes zoster HZ vaccine containing varicella-zoster virus VZV glycoprotein E gE, that can potentially be used to prevent HZ infection, also called shingles. Upon administration, zoster vaccine recombinant, adjuvanted stimulates the host immune system to induce both specific CD4-positive T-cells and antibodies against VZV gE, thereby protecting against infection with HZ. VZV gE, the most common antigen in VZV viral particles, plays a key role in VZV infection. Compared to live-attenuated vaccines, the subunit vaccine prevents the risk of vaccine-induced HZ in immunocompromised patients.
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