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Chemical structure of Troparil

Troparil is a chemical compound that belongs to the class of tropane-based drugs. It is primarily known for its potential use as a stimulant and a psychostimulant medication. Troparil is chemically related to cocaine and has been the subject of research due to its psychoactive properties.

Chemical Structure

Troparil has the following chemical structure:


Troparil acts as a dopamine reuptake inhibitor, similar to cocaine. It inhibits the reuptake of dopamine in the brain, leading to increased dopamine levels in the synaptic cleft. This increase in dopamine is associated with the rewarding and stimulating effects of the drug.

Research and Uses

Troparil has been studied in the context of research into psychostimulant medications and their potential therapeutic applications. However, it is important to note that Troparil is not approved for medical use in most countries due to its potential for abuse and addiction.

Legal Status

The legal status of Troparil varies from country to country. In many places, it is classified as a controlled substance due to its similarity to cocaine and potential for misuse.

Risks and Side Effects

The use of Troparil is associated with several risks and potential side effects, including:

  • Addiction and dependence
  • Cardiovascular effects, such as increased heart rate and blood pressure
  • Anxiety and agitation
  • Insomnia
  • Psychiatric disturbances


Troparil is a stimulant drug used in scientific research. Troparil is a phenyltropane-based dopamine reuptake inhibitor (DRI) that is derived from methylecgonidine. Troparil is a few times more potent than cocaine as a dopamine reuptake inhibitor, but is less potent as a serotonin reuptake inhibitor, and has a duration spanning a few times longer, since the phenyl ring is directly connected to the tropane ring through a non-hydrolyzable carbon-carbon bond. The lack of an ester linkage removes the local anesthetic action from the drug, so troparil is a pure stimulant. This change in activity also makes troparil slightly less cardiotoxic than cocaine. The most commonly used form of troparil is the tartrate salt.


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