Troparil

An overview of Troparil, its uses, and related information

Chemical structure of Troparil

Troparil is a synthetic stimulant drug of the phenyltropane class. It is primarily known for its potential use in scientific research and its effects on the central nervous system. Troparil is structurally related to cocaine and acts as a dopamine reuptake inhibitor, which leads to increased levels of dopamine in the brain.

Pharmacology[edit | edit source]

Troparil functions by inhibiting the dopamine transporter (DAT), which prevents the reuptake of dopamine into presynaptic neurons. This action results in elevated extracellular concentrations of dopamine, leading to enhanced dopaminergic neurotransmission. The increased dopamine levels are associated with the stimulant effects of Troparil, which include increased alertness, euphoria, and enhanced cognitive function.

Potential Uses[edit | edit source]

Troparil has been studied for its potential applications in various fields:

Research Tool: Due to its ability to selectively inhibit dopamine reuptake, Troparil is used in scientific research to study the dopaminergic system and its role in various neurological and psychiatric disorders.

Medical Imaging: Troparil has been investigated as a radioligand in positron emission tomography (PET) imaging to study the distribution and density of dopamine transporters in the brain.

Safety and Legal Status[edit | edit source]

Troparil is not approved for medical use in humans and is primarily used in research settings. Its legal status varies by country, and it is often classified as a controlled substance due to its structural similarity to cocaine and potential for abuse.

History[edit | edit source]

Troparil was first synthesized in the 1970s as part of efforts to develop non-addictive analogs of cocaine. Researchers aimed to create compounds that retained the stimulant effects of cocaine without its addictive properties. Although Troparil has not been developed into a therapeutic drug, it remains of interest in scientific research.

Search WikiMD

Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD

WikiMD's Wellness Encyclopedia

Let Food Be Thy Medicine
Medicine Thy Food - Hippocrates

Translate this page: - East Asian 中文, 日本, 한국어, South Asian हिन्दी, தமிழ், తెలుగు, Urdu, ಕನ್ನಡ, Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, বাংলা
European español, Deutsch, français, Greek, português do Brasil, polski, română, русский, Nederlands, norsk, svenska, suomi, Italian
Middle Eastern & African عربى, Turkish, Persian, Hebrew, Afrikaans, isiZulu, Kiswahili,
Other Bulgarian, Hungarian, Czech, Swedish, മലയാളം, मराठी, ਪੰਜਾਬੀ, ગુજરાતી, Portuguese, Ukrainian

Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.