1,2-Wittig rearrangement - brief summary
A 1,2-Wittig rearrangement is a categorization of chemical reactions in organic chemistry, and consists of a 1,2-rearrangement of an ether with an alkyllithium compound. The reaction is named for Nobel Prize winning chemist Georg Wittig. The intermediate product is an alkoxy lithium salt and the final product an alcohol. When R is a good leaving group and electron withdrawing functional group such as a cyanide (CN) group, this group is eliminated and the corresponding ketone is formed.
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