From WikiMD's Food, Medicine & Wellness Encyclopedia

1,3-Benzodioxolyl-N-ethylpentanamine, also known as Ethylone, is a synthetic compound that belongs to the substituted cathinone family, which is a group of psychoactive compounds. It is closely related to compounds such as methylone and MDMA (3,4-methylenedioxymethamphetamine), sharing a similar chemical structure with the benzodioxole group attached to an amphetamine backbone. Ethylone acts as a psychoactive drug that has stimulant and entactogenic effects.

Chemistry[edit | edit source]

Ethylone is a member of the substituted cathinone family, which itself is a broad category of amphetamine analogues. The chemical name for Ethylone is 1,3-Benzodioxolyl-N-ethylpentanamine. It features a core phenethylamine structure with an alkyl group attached to the alpha carbon and an oxygen group attached to the beta carbon. The presence of the benzodioxole group is what distinguishes Ethylone and its relatives from other phenethylamines.

Pharmacology[edit | edit source]

The pharmacological action of Ethylone is primarily due to its function as a dopamine, serotonin, and norepinephrine reuptake inhibitor and releaser, similar to other compounds in its class. This action leads to increased concentrations of these neurotransmitters in the brain, resulting in stimulant and euphoric effects. The exact mechanism of action is similar to that of MDMA, although the subjective effects and potency can vary significantly.

Effects[edit | edit source]

Users of Ethylone may experience a range of effects, including euphoria, increased energy, empathy, and altered sensory perception. However, like all psychoactive substances, it also poses risks of adverse effects, such as anxiety, paranoia, and physiological effects like increased heart rate and blood pressure. The effects can vary based on dosage, individual physiology, and purity of the substance.

Legal Status[edit | edit source]

The legal status of Ethylone varies by country and region. It has been listed as a controlled substance in some countries due to its potential for abuse and similarity to other controlled substances like MDMA. In jurisdictions where it is not specifically listed as a controlled substance, its sale and possession might still be regulated under analogue drug laws.

Safety[edit | edit source]

Due to its relatively recent appearance on the recreational drug market, the long-term health effects of Ethylone use are not well understood. Users should exercise caution and be aware of the legal and health risks associated with its use. Harm reduction practices, such as using test kits to verify the substance's identity and starting with lower doses, are recommended to mitigate potential risks.


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Contributors: Prab R. Tumpati, MD