1,8-cineole

A natural organic compound found in essential oils

1,8-cineole

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1,8-Cineole, also known as eucalyptol, is a natural organic compound that is a colorless liquid. It is a monoterpenoid and an ether, and it is a major component of the essential oil of eucalyptus leaves. 1,8-Cineole is known for its distinctive, refreshing aroma and is used in a variety of applications, including aromatherapy, pharmaceuticals, and flavoring agents.

Chemical Structure and Properties

1,8-Cineole has the chemical formula C₁₀H₁₈O and a molecular weight of 154.25 g/mol. It is a bicyclic monoterpenoid ether, characterized by a 2-oxabicyclo[2.2.2]octane structure. The compound is relatively stable and has a boiling point of 176 °C (349 °F).

Occurrence

1,8-Cineole is found in the essential oils of several plants, most notably in the leaves of the eucalyptus tree, from which it derives its common name, eucalyptol. It is also present in other aromatic plants such as rosemary, sage, and tea tree.

Uses

1,8-Cineole is widely used in the following areas:

• Aromatherapy: Due to its pleasant aroma, 1,8-cineole is used in aromatherapy to promote relaxation and relieve stress.
• Pharmaceuticals: It has been used in cough suppressants and decongestants due to its ability to reduce mucus and ease breathing.
• Flavoring and Fragrance: 1,8-Cineole is used as a flavoring agent in food products and as a fragrance in perfumes and cosmetics.

Pharmacological Effects

1,8-Cineole has been studied for its potential therapeutic effects. It exhibits anti-inflammatory, analgesic, and antimicrobial properties. Research suggests that it may be beneficial in treating respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD).

Safety and Toxicity

1,8-Cineole is generally recognized as safe (GRAS) when used in food and cosmetics. However, it should be used with caution, as high concentrations can cause irritation or adverse reactions in sensitive individuals.

Also see

• Eucalyptus oil
• Monoterpenes
• Essential oils
• Aromatherapy
• Phytotherapy