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1-Bromopropane (1-BP), also known as n-propyl bromide or nPB, is a brominated hydrocarbon with the chemical formula C3H7Br. It is used as a solvent, particularly in the electronics industry for cleaning and degreasing, as well as in the pharmaceutical industry and in synthetic organic chemistry as a reaction medium. 1-Bromopropane is a colorless liquid that is less dense than water and has a high boiling point relative to its molecular weight.

Properties[edit | edit source]

1-Bromopropane has a boiling point of approximately 71°C and a molecular weight of 122.99 g/mol. It is a nonpolar solvent, which makes it effective at dissolving a wide range of organic compounds. Its physical properties, such as low viscosity and high volatility, make it useful in applications requiring rapid drying and minimal residue.

Uses[edit | edit source]

1-Bromopropane is utilized in various industries due to its solvent properties. In the electronics industry, it is used for precision cleaning of circuits and components. It is also employed in the pharmaceutical industry for the extraction and purification of drugs. In synthetic organic chemistry, 1-BP serves as a medium for carrying out various chemical reactions.

Health and Safety[edit | edit source]

Exposure to 1-bromopropane can occur through inhalation, ingestion, or skin contact. It has been associated with a range of health effects, including neurological symptoms such as dizziness, headaches, and numbness in the extremities. Long-term exposure has been linked to more serious health issues, including reproductive toxicity and cancer. As a result, its use is regulated in many countries, and safety measures such as proper ventilation and the use of personal protective equipment are recommended when handling this chemical.

Regulation[edit | edit source]

Due to its potential health risks, the use and handling of 1-bromopropane are subject to regulation by various health and safety organizations worldwide. In the United States, the Occupational Safety and Health Administration (OSHA) and the Environmental Protection Agency (EPA) have set guidelines and limits for exposure to 1-bromopropane in the workplace and the environment.

Environmental Impact[edit | edit source]

1-Bromopropane is considered a volatile organic compound (VOC) and can contribute to air pollution. It has the potential to form ground-level ozone and other photochemical oxidants when released into the atmosphere. Proper disposal and handling procedures are important to minimize its environmental impact.


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Contributors: Prab R. Tumpati, MD