111In

111Indium (111In) is a radioisotope of indium characterized by a half-life of 2.8 days and is used in nuclear medicine for imaging and therapy. It emits both gamma radiation and Auger electrons.

Production

111In is produced in a cyclotron by the proton irradiation of cadmium. The resulting 111mCd decays to 111In by electron capture.

Medical uses

111In is used in nuclear medicine for imaging and therapy. It is used in radiopharmaceuticals such as Octreoscan (111In-DTPA-octreotide) for imaging neuroendocrine tumors, and ProstaScint (111In-capromab pendetide) for imaging prostate cancer.

Decay

111In decays by electron capture to 111Cd with a half-life of 2.8 days. The decay is accompanied by the emission of gamma radiation with energies of 171 and 245 keV, and Auger electrons.

Safety

As with all radioisotopes, handling 111In requires precautions to avoid radiation exposure. These include the use of lead shielding and radiation monitoring devices.

See also

• Indium
• Radioisotope
• Nuclear medicine
• Radiopharmaceutical
• Cyclotron

111In Resources
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