2,2,2-Trifluoroethanol

2,2,2-Trifluoroethanol is a chemical compound that belongs to the fluoroalcohol family. It is a colorless, water-miscible liquid with a strong, characteristic odor. It is often used in the pharmaceutical industry and in organic chemistry due to its unique properties.

Chemical Properties

2,2,2-Trifluoroethanol is a polar solvent that has a higher boiling point and lower volatility compared to ethanol. It is highly miscible with water and many organic solvents, making it a useful solvent in many chemical reactions. It also has a high dielectric constant, which allows it to dissolve a wide range of ionic compounds.

Uses

In the pharmaceutical industry, 2,2,2-Trifluoroethanol is used as a solvent for the synthesis of drugs. It is also used in the production of fluorinated compounds, which are often used in the manufacture of fluorocarbon resins and fluoropolymers.

In organic chemistry, 2,2,2-Trifluoroethanol is used as a solvent for NMR spectroscopy due to its ability to dissolve a wide range of compounds and its compatibility with most NMR solvents. It is also used in peptide synthesis and protein folding studies due to its ability to stabilize alpha-helices.

Safety

2,2,2-Trifluoroethanol is a highly flammable liquid and vapor. It can cause burns and eye damage, and may be harmful if inhaled. It is recommended to use personal protective equipment when handling this chemical.

See Also

• Fluoroalcohol
• Polar solvent
• Pharmaceutical industry
• Organic chemistry