Biochemistry

From WikiMD's Wellness Encyclopedia

Biochemistry, at its core, delves into the intricate chemical processes that orchestrate life within every living organism. Serving as a nexus between biology and chemistry, this scientific discipline illuminates the chemical and physicochemical undertakings that sustain living organisms.

NMR sample

The Essence of Biochemistry[edit | edit source]

Biochemists wield the knowledge and techniques of biochemical operations to decode and address challenges in biology. Their expertise unravels the mysteries of how biological molecules are instrumental in the processes within and between living cells.[1] This understanding, in turn, deepens our grasp of the architecture and functionality of tissues, organs, and entire organisms.[2]

Branching Out: Sub-disciplines of Biochemistry[edit | edit source]

The multifaceted realm of biochemistry splinters into three primary sectors:

Throughout the latter half of the 20th century, biochemistry's triumphant strides in these domains have elucidated numerous living processes. Today, its methodologies and research avenues permeate almost all life science sectors, broadening our comprehension of life's tapestry.[3]

Biochemistry and Molecular Biology: Two Sides of the Same Coin[edit | edit source]

While biochemistry delves deep into the chemistry of life, it shares a symbiotic relationship with molecular biology. The latter seeks to unravel the molecular mechanisms wherein genetic codes encrypted within DNA govern life's processes.[4]

The Foundations of Biochemistry[edit | edit source]

At the heart of biochemistry lies the study of biological macromolecules, including:

These entities shape the cellular structure and are pivotal to life's functions.[5] However, the cell's chemistry is not limited to these giants. It also hinges on the interactions and reactions of minuscule molecules and ions, both inorganic (like water and metal ions) and organic (such as amino acids, the building blocks for protein synthesis).[6] The intricate choreography by which cells extract energy through chemical reactions from their surroundings is termed metabolism.

Applications of Biochemistry[edit | edit source]

The revelations of biochemistry find profound applications in:

For an in-depth exploration of terms related to biochemistry, refer to the Glossary of biochemistry and for a more detailed terminology list, see the Glossary of Biochemistry terms.

  1. Karp (2009), p. 2.
  2. Miller (2012). p. 62.
  3. Voet (2005), p. 3.
  4. Astbury (1961), p. 1124.
  5. Eldra (2007), p. 45.
  6. Marks (2012), Chapter 14.
  7. Finkel (2009), pp. 1–4.
  8. UNICEF (2010), pp. 61, 75.
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Contributors: Prab R. Tumpati, MD