Human Genome Project

From WikiMD's Wellnesspedia

Human Genome Project is an international scientific research project with the goal of determining the sequence of nucleotide base pairs that make up human DNA, and of identifying and mapping all of the genes of the human genome from both a physical and a functional standpoint. It remains the world's largest collaborative biological project.

History[edit | edit source]

The Human Genome Project originally aimed to map the nucleotides contained in a haploid reference human genome (more than three billion). The "genome" of any given individual is unique; mapping the "human genome" involves sequencing multiple variations of each gene.

Goals[edit | edit source]

The primary goal of the HGP was to produce a complete and accurate sequence of the 3 billion DNA base pairs that make up the human genome and to find all of the estimated 20,000 to 25,000 human genes. The project also aimed to sequence the genomes of several other organisms that are important to medical research, such as the mouse and the fruit fly.

Methods[edit | edit source]

Two main strategies were initially considered for sequencing the genome. The first approach was "map-first, sequence-later". The second approach was "sequence-first, map-later".

Results[edit | edit source]

The Human Genome Project was declared complete in April 2003. An initial rough draft of the human genome was available in June 2000 and by February 2001 a working draft had been completed and published followed by the final sequencing mapping of the human genome on April 14, 2003.

Implications[edit | edit source]

The implications of the Human Genome Project are enormous. It has the potential to revolutionize the fields of medicine, biotechnology, and the life sciences in general.

See also[edit | edit source]

References[edit | edit source]


Human Genome Project Resources

Find a healthcare provider anywhere in the world quickly and easily!

Wiki.png

Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD


Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro) available.
Advertise on WikiMD

WikiMD is not a substitute for professional medical advice. See full disclaimer.

Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.


Contributors: Admin, Prab R. Tumpati, MD