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2,3,4,5-Tetramethoxyamphetamine (also known as Aleph-7) is a lesser-known psychedelic drug and a substituted amphetamine. It is structurally related to amphetamine and other psychedelic phenethylamines.

Chemistry[edit | edit source]

2,3,4,5-Tetramethoxyamphetamine is a compound of the phenethylamine class. It is classified as a substituted amphetamine, which means it contains a phenethylamine unit with an additional methyl group on the alpha carbon. The molecule is further substituted with four methoxy groups at R2, R3, R4, and R5 of its phenyl ring.

Pharmacology[edit | edit source]

The pharmacological properties of 2,3,4,5-Tetramethoxyamphetamine are not well-studied. However, it is known to act as a serotonin receptor agonist, similar to other psychedelic amphetamines. The drug's effects are thought to be caused by its efficacy at the 5-HT2A receptor site.

Effects[edit | edit source]

The effects of 2,3,4,5-Tetramethoxyamphetamine are similar to those of other psychedelic amphetamines. These can include hallucinations, altered thinking processes, closed and open eye visuals, synesthesia, an altered sense of time, and spiritual experiences. The specific effects can vary greatly depending on the dose and the individual's personal chemistry.

Legality[edit | edit source]

2,3,4,5-Tetramethoxyamphetamine is a Schedule I controlled substance in the United States. This means it is illegal to manufacture, buy, possess, or distribute without a license from the Drug Enforcement Administration.

See also[edit | edit source]


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Contributors: Prab R. Tumpati, MD