2,3-Dichlorophenylpiperazine

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2,3-Dichlorophenylpiperazine (2,3-DCPP or DCPP) is a chemical compound in the piperazine family. It is a less commonly known analogue of the drug phenylpiperazine, and is a potent serotonin releasing agent.

Chemistry[edit | edit source]

2,3-Dichlorophenylpiperazine is a derivative of piperazine, which is a six-membered ring containing two nitrogen atoms at opposite positions in the ring. The 2,3-dichlorophenyl moiety is a phenyl ring substituted at positions 2 and 3 with chlorine atoms.

Pharmacology[edit | edit source]

2,3-Dichlorophenylpiperazine is a potent serotonin releasing agent, with selectivity for the 5-HT2A and 5-HT2C receptors. It is thought to be responsible for the release of serotonin, a neurotransmitter that plays a key role in mood regulation, sleep, and other functions in the body.

Toxicity[edit | edit source]

The toxicity of 2,3-dichlorophenylpiperazine is not well studied, but it is likely to be similar to that of other phenylpiperazines. These compounds can cause a range of adverse effects, including anxiety, restlessness, and potentially serious cardiac effects.

Legal Status[edit | edit source]

In many countries, 2,3-dichlorophenylpiperazine is a controlled substance due to its potential for abuse and its similarity to other controlled phenylpiperazines.

See Also[edit | edit source]

References[edit | edit source]


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Contributors: Prab R. Tumpati, MD