2-APBT

Chemical compound

2-APBT

Chemical structure of 2-APBT

2-APBT, or 2-(Aminopropyl)benzothiophene, is a synthetic compound that belongs to the class of substituted amphetamines. It is structurally related to other psychoactive substances such as amphetamine and methamphetamine, but it features a benzothiophene ring system instead of the phenethylamine core.

Chemical Structure and Properties

2-APBT is characterized by the presence of a benzothiophene ring, which is a bicyclic structure consisting of a benzene ring fused to a thiophene ring. The compound also contains an aminopropyl side chain, which is a common feature in many psychoactive substances. This structural modification is believed to influence the compound's pharmacological properties.

The molecular formula of 2-APBT is C11H13NS, and it has a molar mass of 191.29 g/mol. The presence of the sulfur atom in the thiophene ring distinguishes it from other amphetamine derivatives, potentially affecting its binding affinity and activity at various receptor sites in the brain.

Pharmacology

The pharmacological profile of 2-APBT is not well-documented, but it is presumed to act as a central nervous system stimulant, similar to other amphetamine derivatives. It may exert its effects by increasing the release of monoamine neurotransmitters such as dopamine, norepinephrine, and serotonin in the brain. This action is typically associated with increased alertness, energy, and euphoria.

Due to its structural similarity to other psychoactive substances, 2-APBT may also have potential for abuse and could pose risks of addiction and adverse effects. However, detailed studies on its pharmacokinetics, metabolism, and long-term effects are lacking.

Legal Status

The legal status of 2-APBT varies by country. In some jurisdictions, it may be classified as a controlled substance due to its potential for abuse and lack of medical use. In others, it may not be specifically regulated, although it could still fall under analog laws that control substances similar to known illegal drugs.

Synthesis

The synthesis of 2-APBT involves the introduction of an aminopropyl group to a benzothiophene core. This process typically requires advanced knowledge of organic chemistry and access to specialized reagents and equipment. The synthesis pathways may vary, but they generally involve the formation of the benzothiophene ring followed by the addition of the aminopropyl side chain.

Potential Applications

While 2-APBT is primarily of interest in the context of recreational drug use, it may also have potential applications in scientific research. Studies on its pharmacological properties could contribute to a better understanding of the structure-activity relationships of amphetamine-like compounds and their effects on the central nervous system.

Related pages

• Amphetamine
• Methamphetamine
• Substituted amphetamines
• Psychoactive drug