2-Methoxyethyl-18-methoxycoronaridinate

From WikiMD's Food, Medicine & Wellness Encyclopedia

2-Methoxyethyl-18-methoxycoronaridinate is a chemical compound that belongs to the class of organic compounds known as alkaloids and derivatives. These are naturally occurring chemical compounds that contain mostly basic nitrogen atoms. This group also includes some related compounds with neutral and even weakly acidic properties.

Chemical Structure[edit | edit source]

The chemical structure of 2-Methoxyethyl-18-methoxycoronaridinate consists of a coronaridine core, which is a pentacyclic structure that includes a seven-membered ring fused to a decahydroquinoline ring system. The coronaridine core is substituted at the 18-position with a methoxy group and at the 2-position with a methoxyethyl group.

Synthesis[edit | edit source]

The synthesis of 2-Methoxyethyl-18-methoxycoronaridinate involves the reaction of coronaridine with methanol in the presence of a strong acid to form the 18-methoxycoronaridinate. This is then reacted with 2-methoxyethanol in the presence of a base to form the final product.

Properties[edit | edit source]

2-Methoxyethyl-18-methoxycoronaridinate is a solid at room temperature. It is soluble in organic solvents such as chloroform, ethanol, and dimethyl sulfoxide (DMSO). The compound is stable under normal conditions but can decompose under high heat or in the presence of strong acids or bases.

Applications[edit | edit source]

While the specific applications of 2-Methoxyethyl-18-methoxycoronaridinate are not well-documented, alkaloids and their derivatives have a wide range of uses in the pharmaceutical industry. They are often used as starting materials in the synthesis of various drugs, including analgesics, antimalarials, and antibiotics.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD