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2-MMC structure

2-Methylmethcathinone (2-MMC) is a psychoactive substance that belongs to the substituted cathinone family, which includes compounds structurally related to cathinone, the active component found in the khat plant. As a derivative of cathinone, 2-MMC shares similar chemical properties and mechanisms of action but differs due to the addition of a methyl group at the second carbon atom of the phenethylamine core. This modification can significantly alter the compound's pharmacological profile, affecting its potency, duration of action, and subjective effects.

Chemistry[edit | edit source]

2-Methylmethcathinone is a synthetic molecule of the cathinone class. Cathinones are structurally similar to amphetamines, differing primarily by the presence of a β-keto group on the phenethylamine core. The molecular formula of 2-MMC is C11H15NO, indicating the addition of a methyl group at the 2nd position of the carbon chain, which distinguishes it from methcathinone and other cathinone derivatives.

Pharmacology[edit | edit source]

The pharmacological action of 2-MMC, like other cathinones, is primarily characterized by its function as a central nervous system stimulant. It is believed to work by increasing the release of dopamine, norepinephrine, and serotonin and inhibiting their reuptake. This action results in increased neurotransmitter levels in the brain, leading to stimulant and euphoric effects. However, the exact pharmacological profile of 2-MMC, including its potency and selectivity for various neurotransmitter systems, may vary from other cathinones due to its structural differences.

Effects[edit | edit source]

Users of 2-Methylmethcathinone may experience a range of effects, which can vary based on dosage, individual physiology, and other factors. Common reported effects include:

  • Increased energy and alertness
  • Euphoria
  • Enhanced sociability
  • Increased heart rate and blood pressure
  • Diminished appetite

However, adverse effects are also possible, particularly with higher doses or prolonged use, including:

  • Anxiety and paranoia
  • Insomnia
  • Nausea and vomiting
  • Increased risk of cardiovascular problems
  • Potential for dependence and abuse

Legal Status[edit | edit source]

The legal status of 2-Methylmethcathinone varies by country and region. In some jurisdictions, it is a controlled substance, making its manufacture, distribution, and possession illegal. In others, it may fall under analogue acts or temporary control measures pending further research into its effects and potential risks. The rapidly evolving legal landscape surrounding synthetic cathinones makes it important for individuals to stay informed about the current regulations in their area.

See Also[edit | edit source]


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Contributors: Prab R. Tumpati, MD