2-Naphthylmethcathinone

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Synthetic stimulant drug


2-Naphthylmethcathinone
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2-Naphthylmethcathinone (also known as 2-NMC or Naphyrone) is a synthetic stimulant drug of the cathinone class. It is chemically related to other synthetic cathinones such as mephedrone and methcathinone.

Chemical Structure and Properties[edit | edit source]

2-Naphthylmethcathinone is a derivative of cathinone, which is a naturally occurring stimulant found in the khat plant. The chemical structure of 2-NMC includes a naphthyl group attached to the cathinone backbone, which distinguishes it from other cathinones. This structural modification is believed to influence its pharmacological properties.

Chemical structure of 2-Naphthylmethcathinone

The IUPAC name for 2-NMC is 1-(2-naphthyl)-2-(methylamino)propan-1-one. It has a molecular formula of C14H15NO and a molar mass of 213.28 g/mol.

Pharmacology[edit | edit source]

2-Naphthylmethcathinone acts as a stimulant in the central nervous system. It is believed to exert its effects by increasing the levels of neurotransmitters such as dopamine, norepinephrine, and serotonin in the brain. This action is similar to that of other stimulant drugs, leading to increased alertness, energy, and euphoria.

The exact mechanism of action of 2-NMC is not fully understood, but it is thought to involve the inhibition of monoamine transporters, which prevents the reuptake of neurotransmitters into presynaptic neurons.

Legal Status[edit | edit source]

The legal status of 2-Naphthylmethcathinone varies by country. In many jurisdictions, it is classified as a controlled substance due to its potential for abuse and lack of accepted medical use. It is often included in legislation targeting synthetic cathinones and other designer drugs.

Health Risks and Side Effects[edit | edit source]

The use of 2-Naphthylmethcathinone can pose significant health risks. Potential side effects include increased heart rate, hypertension, anxiety, agitation, and insomnia. In some cases, more severe effects such as psychosis, seizures, and cardiovascular complications have been reported.

Due to the lack of clinical studies, the long-term effects of 2-NMC use are not well-documented, but it is generally advised to avoid its use due to the potential for harm.

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