From WikiMD's Food, Medicine & Wellness Encyclopedia

2-Pyridylethylamine is a biogenic amine that acts as a selective agonist for the histamine H1 receptor. It is used in scientific research to study the effects of this receptor.

Chemistry[edit | edit source]

2-Pyridylethylamine is a derivative of pyridine, with an ethylamine group attached to the second carbon in the ring. Its chemical formula is C7H10N2 and its molecular weight is 122.17 g/mol. It is a colorless liquid at room temperature.

Pharmacology[edit | edit source]

2-Pyridylethylamine is a selective agonist for the histamine H1 receptor. This means it can bind to this receptor and activate it, mimicking the effects of histamine. The H1 receptor is one of four known histamine receptors and is particularly involved in inflammatory responses and the regulation of immune system functions.

Uses in Research[edit | edit source]

In scientific research, 2-Pyridylethylamine is often used to study the effects of the histamine H1 receptor. For example, it can be used in in vitro studies to determine how activation of this receptor affects cell behavior. It can also be used in animal models to study the effects of H1 receptor activation in a whole organism.

Safety[edit | edit source]

As with any chemical, proper safety precautions should be taken when handling 2-Pyridylethylamine. It can cause skin and eye irritation, and may be harmful if swallowed or inhaled.

See Also[edit | edit source]


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Contributors: Prab R. Tumpati, MD