2C-iP

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2C-iP is a psychedelic and phenethylamine of the 2C family. It was first synthesized by Alexander Shulgin and described in his book PiHKAL: A Chemical Love Story.

History[edit | edit source]

2C-iP was first synthesized by Alexander Shulgin. The synthesis and effects of 2C-iP are documented in Shulgin's book PiHKAL. Shulgin's interest in the 2C family of drugs stemmed from his earlier work with mescaline, a naturally occurring psychedelic found in certain cacti.

Chemistry[edit | edit source]

2C-iP, or 2,5-dimethoxy-4-(i)-propylphenethylamine, is a member of the 2C family of phenethylamines, specifically the 2C-i family. Its structure consists of a six-membered benzene ring bound to an amino (NH2) group through an ethyl chain. 2C-iP contains methoxy functional groups CH3O- attached to carbons R2 and R5 as well as a propyl chain attached to carbon R4 of the phenyl ring.

Pharmacology[edit | edit source]

Like other 2C drugs, 2C-iP acts as a serotonin receptor agonist. It is thought to work primarily by binding to the 5-HT2A receptor, which is involved in regulating mood, anxiety, and perception. However, the exact mechanisms of action are not fully understood.

Effects[edit | edit source]

The effects of 2C-iP are similar to other 2C drugs, and include hallucinations, altered perception of time, enhanced introspection, and increased empathy. However, the effects can vary greatly depending on the individual, dosage, and set and setting.

Legal status[edit | edit source]

The legal status of 2C-iP varies by country. In the United States, it is not specifically listed as a controlled substance, but it may be considered an analog of other illegal drugs under the Federal Analogue Act.

See also[edit | edit source]

Template:Psychedelic phenethylamines Template:2C (psychedelics) Template:Alexander Shulgin

2C-iP Resources

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Contributors: Prab R. Tumpati, MD