3,5-Difluoromethcathinone

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3,5-Difluoromethcathinone (also known as 3,5-DFMC) is a psychoactive drug of the cathinone class. It is a fluorinated analogue of methcathinone, a stimulant substance.

Chemistry[edit | edit source]

3,5-Difluoromethcathinone is a synthetic cathinone. Cathinones are structurally similar to amphetamines, they contain a phenethylamine core featuring a phenyl ring bound to an amino (NH2) group through an ethyl chain with an additional methyl substitution at Rα. 3,5-DFMC contains two additional substitutions at R3 and R5 of the phenyl ring with fluorine groups.

Pharmacology[edit | edit source]

The pharmacology of 3,5-difluoromethcathinone is largely unknown. As a cathinone, it is presumed to act as a norepinephrine-dopamine reuptake inhibitor (NDRI), but it has not been formally studied. The fluorine substitutions at the 3 and 5 positions of the phenyl ring potentially alter the pharmacokinetics of the substance, but the exact effects are not known.

Effects[edit | edit source]

The effects of 3,5-difluoromethcathinone in humans are not well documented. It is likely to produce effects similar to other stimulants, including increased energy, focus, and sociability, as well as potential negative effects such as increased heart rate, blood pressure, and risk of addiction. However, due to the lack of research, all potential effects are speculative.

Legal Status[edit | edit source]

The legal status of 3,5-difluoromethcathinone varies by country. In many jurisdictions, it is not explicitly controlled, but it may fall under analogue laws which make substances with similar structures to controlled drugs, illegal.

See Also[edit | edit source]

References[edit | edit source]


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Contributors: Prab R. Tumpati, MD