3-Hydroxyphenazepam

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3-Hydroxyphenazepam is a benzodiazepine with anxiolytic, anticonvulsant, hypnotic, sedative, skeletal muscle relaxant, and amnestic properties. It is an active metabolite of phenazepam, as well as the active metabolite of the benzodiazepine brompheniramine and quinazolinone.

Pharmacology[edit | edit source]

3-Hydroxyphenazepam is a benzodiazepine with anxiolytic, anticonvulsant, hypnotic, sedative, skeletal muscle relaxant, and amnestic properties. It is an active metabolite of phenazepam, as well as the active metabolite of the benzodiazepine brompheniramine and quinazolinone.

Chemistry[edit | edit source]

3-Hydroxyphenazepam is a benzodiazepine with a phenyl ring fused to a diazepine ring. This forms a seven-membered ring with two nitrogen constituents located at R1 and R4. At carbon R5, the phenyl ring is substituted with a hydroxy (OH) group.

Legal Status[edit | edit source]

In the United States, 3-Hydroxyphenazepam is classified as a Schedule I controlled substance, which makes it illegal to manufacture, distribute, or possess without a license.

See Also[edit | edit source]

3-Hydroxyphenazepam Resources
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Contributors: Prab R. Tumpati, MD