3-Methoxytyramine
A metabolite of dopamine
| Chemical Compound | |
|---|---|
| Identifiers | |
| CAS Number | |
| PubChem CID | |
| ChemSpider ID | |
| UNII | |
| ChEBI | |
| ChEMBL | |
| Properties | |
| Chemical Formula | |
| Molar Mass | |
| Appearance | |
| Density | |
| Melting Point | |
| Boiling Point | |
| Hazards | |
| GHS Pictograms | [[File:|50px]] |
| GHS Signal Word | |
| GHS Hazard Statements | |
| NFPA 704 | [[File:|50px]] |
| References | |
3-Methoxytyramine (3-MT) is a catecholamine and a metabolite of the neurotransmitter dopamine. It is formed by the action of the enzyme catechol-O-methyltransferase (COMT) on dopamine.
Biochemistry[edit | edit source]
3-Methoxytyramine is produced in the brain and other tissues as part of the dopamine metabolism pathway. When dopamine is released into the synaptic cleft, it can be taken back up into the presynaptic neuron, degraded by monoamine oxidase (MAO), or metabolized by COMT to form 3-MT. This process is part of the regulation of dopamine levels in the central nervous system.
Function[edit | edit source]
While 3-Methoxytyramine was traditionally considered an inactive metabolite, recent research suggests it may have biological activity of its own. It has been proposed to act as a neuromodulator and may influence dopaminergic signaling in the brain. However, the exact physiological role of 3-MT is still under investigation.
Clinical significance[edit | edit source]
The levels of 3-Methoxytyramine in the body can be indicative of certain medical conditions. Elevated levels may be associated with pheochromocytoma, a type of tumor that can affect catecholamine production. Measuring 3-MT levels can be part of the diagnostic process for such conditions.
Synthesis[edit | edit source]
In the laboratory, 3-Methoxytyramine can be synthesized through the methylation of tyramine using methylating agents. This process is useful for research purposes and for the study of its properties and potential effects.
Related pages[edit | edit source]
Gallery[edit | edit source]
Structural formula of 3-Methoxytyramine
3D ball-and-stick model of 3-Methoxytyramine
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
