4',7-Dihydroxyflavone

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4',7-Dihydroxyflavone is a flavone, a type of phenolic chemical compound. It is a bioactive flavone that has been found to have neuroprotective effects.

Chemical Structure[edit | edit source]

The chemical structure of 4',7-Dihydroxyflavone consists of a 15-carbon skeleton that is composed of two phenyl rings (A and B) and a heterocyclic ring (C). This structure is similar to the backbone of flavonoids, the parent compound of flavones. The two hydroxy groups in the molecule are located at the 4' and 7 positions.

Bioactivity[edit | edit source]

4',7-Dihydroxyflavone has been found to have neuroprotective effects. It has been shown to promote the survival of neurons and to increase the levels of brain-derived neurotrophic factor (BDNF), a protein that supports the survival of existing neurons and encourages the growth and differentiation of new neurons and synapses.

Potential Therapeutic Uses[edit | edit source]

Due to its neuroprotective effects, 4',7-Dihydroxyflavone has potential therapeutic uses in the treatment of neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease. However, more research is needed to fully understand its mechanisms of action and to determine its safety and efficacy in humans.

See Also[edit | edit source]

References[edit | edit source]


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Contributors: Prab R. Tumpati, MD