4'-Chlorodeschloroalprazolam

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Chemical compound related to alprazolam


4'-Chlorodeschloroalprazolam is a chemical compound that belongs to the class of triazolobenzodiazepines, which are benzodiazepine derivatives. It is structurally related to alprazolam, a well-known anxiolytic medication.

Chemical Structure[edit | edit source]

Structure of 4'-Chlorodeschloroalprazolam

4'-Chlorodeschloroalprazolam is characterized by the presence of a triazole ring fused to a benzodiazepine core. The compound is distinguished by the substitution of a chlorine atom at the 4' position of the phenyl ring, which is a modification from the parent compound, alprazolam.

Pharmacology[edit | edit source]

4'-Chlorodeschloroalprazolam, like other benzodiazepines, is believed to exert its effects by enhancing the activity of the gamma-aminobutyric acid (GABA) neurotransmitter in the brain. This action is mediated through the GABA_A receptor, leading to increased inhibitory neurotransmission and resulting in sedative, anxiolytic, and muscle relaxant effects.

Legal Status[edit | edit source]

The legal status of 4'-Chlorodeschloroalprazolam varies by country. In many jurisdictions, it may be classified as a controlled substance due to its structural similarity to other regulated benzodiazepines. It is important for researchers and healthcare professionals to be aware of the specific regulations governing its use and distribution in their region.

Potential Uses and Research[edit | edit source]

While 4'-Chlorodeschloroalprazolam is not approved for medical use, it may be of interest in research settings for studying the pharmacological properties of benzodiazepine analogs. Researchers may investigate its binding affinity to the GABA_A receptor, its metabolic pathways, and its potential therapeutic applications or risks.

Safety and Toxicity[edit | edit source]

As with other benzodiazepines, there is a potential for abuse, dependence, and withdrawal symptoms associated with 4'-Chlorodeschloroalprazolam. The compound's safety profile has not been extensively studied, and caution is advised when handling or researching this substance.

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Contributors: Prab R. Tumpati, MD