4-Anisaldehyde

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4-Anisaldehyde[edit | edit source]

4-Anisaldehyde is an organic compound with the chemical formula C₈H₈O₂. It is also known as p-anisaldehyde or 4-methoxybenzaldehyde. This compound belongs to the class of aldehydes and is commonly used in the synthesis of various pharmaceuticals, fragrances, and flavoring agents.

Properties[edit | edit source]

4-Anisaldehyde is a colorless to pale yellow liquid with a strong, sweet, and floral odor. It has a molecular weight of 136.15 g/mol and a boiling point of 248-250 °C. The compound is sparingly soluble in water but highly soluble in organic solvents such as ethanol and ether.

Synthesis[edit | edit source]

4-Anisaldehyde can be synthesized through several methods. One common approach involves the oxidation of anisole using an oxidizing agent such as chromic acid or potassium permanganate. Another method involves the reaction of anisole with formaldehyde in the presence of an acid catalyst.

Applications[edit | edit source]

Pharmaceuticals[edit | edit source]

4-Anisaldehyde is widely used in the pharmaceutical industry as an intermediate in the synthesis of various drugs. It serves as a building block for the production of antihistamines, anti-inflammatory agents, and antifungal drugs.

Fragrances[edit | edit source]

Due to its pleasant floral scent, 4-Anisaldehyde is extensively used in the fragrance industry. It is a key ingredient in the production of perfumes, soaps, and other personal care products. The compound adds a sweet and powdery note to fragrances, making it a popular choice among perfumers.

Flavoring Agents[edit | edit source]

4-Anisaldehyde is also utilized as a flavoring agent in the food industry. It imparts a sweet, vanilla-like flavor to various food products, including baked goods, beverages, and confectioneries.

Safety[edit | edit source]

4-Anisaldehyde should be handled with care as it may cause irritation to the skin, eyes, and respiratory system. It is recommended to use appropriate protective equipment, such as gloves and goggles, when working with this compound. In case of ingestion or inhalation, immediate medical attention should be sought.

References[edit | edit source]

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD