4-Fluorobutanol

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4-Fluorobutanol


4-Fluorobutanol is a fluorinated compound and an alcohol that is part of the larger family of organic compounds. It is characterized by the presence of a fluorine atom and a hydroxyl group in its molecular structure.

Chemical Structure[edit | edit source]

The chemical structure of 4-Fluorobutanol consists of a four-carbon alkyl chain with a fluorine atom attached to the fourth carbon and a hydroxyl group attached to the first carbon. This structure is what classifies it as a fluorinated alcohol.

Properties[edit | edit source]

4-Fluorobutanol exhibits properties common to both fluorinated compounds and alcohols. The presence of the fluorine atom imparts unique characteristics due to the high electronegativity of fluorine. This results in a polar bond with the carbon atom, which can influence the compound's reactivity and physical properties. The hydroxyl group also contributes to the compound's reactivity and enables it to participate in reactions typical of alcohols.

Synthesis[edit | edit source]

The synthesis of 4-Fluorobutanol typically involves the reaction of a suitable alkene with hydrofluoric acid in the presence of an alcohol. The alkene undergoes addition reaction to incorporate the fluorine atom and the hydroxyl group into the molecular structure.

Applications[edit | edit source]

While 4-Fluorobutanol is primarily of interest in research contexts, potential applications may exist in the synthesis of pharmaceuticals and agrochemicals, where fluorinated alcohols can serve as versatile intermediates.

Safety[edit | edit source]

As with many fluorinated compounds and alcohols, appropriate safety measures should be taken when handling 4-Fluorobutanol. It may be harmful if swallowed, inhaled, or comes into contact with skin.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD