4-HO-MET

4-HO-MET (4-hydroxy-N-methyl-N-ethyltryptamine), also known as methylcybin, metocin, or "Colour", is a lesser-known psychedelic drug. It is a structural and functional analog of psilocin, as well as the 4-hydroxy analog of methylethyltryptamine (MET).

History and usage

4-HO-MET was first synthesized by the famous chemist Alexander Shulgin. In his book TiHKAL (Tryptamines I Have Known and Loved), the dosage is listed as 10-20 mg. The substance is consumed orally, and its effects last 3-6 hours.

Pharmacology

Like other psychedelic drugs, 4-HO-MET is thought to act primarily as a serotonin receptor agonist. This means it binds to and activates certain serotonin receptors in the brain, leading to its psychedelic effects. However, the exact mechanisms of action are not fully understood.

Effects

The effects of 4-HO-MET are similar to other tryptamine-based psychedelics like psilocybin and DMT. These can include visual hallucinations, enhanced colors, altered thinking processes, and a sense of euphoria. However, 4-HO-MET is often reported to be more recreational and less introspective than its more famous counterparts.

Legal status

The legal status of 4-HO-MET varies by country. In the United States, it is not specifically listed as a controlled substance, but it could potentially be considered an analog of psilocin, which is a Schedule I drug.

Safety

As with all psychedelics, 4-HO-MET should be used responsibly. It is not known to be physically addictive, but psychological dependence can occur. There is also the risk of having a "bad trip," which can be a distressing and potentially traumatic experience.

See also

• Tryptamine
• Psychedelic drug
• Alexander Shulgin
• TiHKAL