4-MeO-DMT

4-MeO-DMT

4-MeO-DMT (4-Methoxy-N,N-dimethyltryptamine) is a psychedelic tryptamine compound found in certain plants. It is a structural analog of psilocin and psilocybin, two compounds found in psychedelic mushrooms.

Chemistry

4-MeO-DMT is a synthetic compound of the tryptamine class. Tryptamines share a core structure comprised of a bicylic indole heterocycle attached at R3 to an amino group via an ethyl side chain. 4-MeO-DMT is substituted at R4 of its indole ring with a methoxy (MeO) functional group CH3O−. It also contains two methyl groups CH3- bound to the terminal amine RN of the tryptamine backbone (DMT).

Pharmacology

The pharmacology of 4-MeO-DMT is not well-studied. However, like other tryptamines, it is thought to act as a serotonin agonist at the 5-HT2A receptor. This receptor is involved in the regulation of various functions in the brain, including mood, cognition, and perception. Activation of this receptor by 4-MeO-DMT may lead to its psychedelic effects.

Effects

The effects of 4-MeO-DMT can vary greatly depending on the dose, set and setting, and individual physiology. Common effects reported by users include visual hallucinations, altered thought processes, and a sense of euphoria. Some users also report experiencing negative effects such as anxiety, paranoia, and uncomfortable physical sensations.

Legal Status

The legal status of 4-MeO-DMT varies by country. In some countries, it is a controlled substance, while in others it is legal to possess for personal use. It is always important to understand the legal implications of possessing or using this substance in your specific location.

See Also

• DMT
• Psilocybin
• Tryptamine