4-Methoxybutyrfentanyl

4-Methoxybutyrfentanyl

4-Methoxybutyrfentanyl (4-MeO-BF) is a potent opioid analgesic that is an analog of fentanyl and is sold online as a designer drug. It has been found in opioid overdose deaths in Europe since 2016, and is believed to be several times more potent than morphine.

Chemistry

4-Methoxybutyrfentanyl is a fentanyl analog, meaning it has a similar chemical structure. It is part of the 4-anilidopiperidine class of opioids. The '4-Methoxy' part of its name refers to the methoxy group (OCH3) attached to the 4 position of the phenyl ring. The 'butyr' part of its name refers to the butyryl group (C3H7CO) attached to the nitrogen atom of the piperidine ring.

Pharmacology

Like other opioids, 4-Methoxybutyrfentanyl acts on the mu-opioid receptor to produce its analgesic effects. It is believed to be several times more potent than morphine, although exact potency can vary due to factors such as individual metabolism and tolerance.

Effects

The effects of 4-Methoxybutyrfentanyl are similar to other opioids and include analgesia, sedation, euphoria, constipation, itching and respiratory depression which can be harmful or fatal.

Legal status

4-Methoxybutyrfentanyl is illegal in many countries due to its potential for abuse and high risk of overdose. In the United States, it is a Schedule I controlled substance.

See also

• Fentanyl
• Opioid
• Designer drug