4-methylaminorex

From WikiMD's Food, Medicine & Wellness Encyclopedia

4-Methylaminorex (4-MAR, U4Euh, Ice, Eve) is a stimulant drug of the 2-amino-5-aryloxazoline class that was first synthesized in 1960 by McNeil Laboratories. It is also known as a nootropic due to its cognitive enhancing effects.

Chemistry[edit | edit source]

4-Methylaminorex has a stereochemistry similar to methamphetamine and is related to ephedrine. It is a member of the 2-amino-5-aryloxazoline class of stimulants. The synthesis of 4-Methylaminorex requires a number of chemicals and laboratory equipment, and is considered moderately difficult to perform.

Pharmacology[edit | edit source]

4-Methylaminorex acts as a potent and selective agonist at the norepinephrine and dopamine receptors, with little effect on the serotonin receptors. This results in increased levels of these neurotransmitters in the brain, leading to increased alertness, focus, and euphoria.

Effects[edit | edit source]

The effects of 4-Methylaminorex are similar to those of other stimulants, and include increased energy, focus, and euphoria. However, it also has a number of side effects, including insomnia, anxiety, and potential for addiction.

Legal Status[edit | edit source]

4-Methylaminorex is a Schedule I controlled substance in the United States, and is also controlled in many other countries. This means that it is illegal to manufacture, distribute, or possess without a license.

See Also[edit | edit source]

References[edit | edit source]



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Contributors: Prab R. Tumpati, MD