5-(2-Cyclohexylideneethyl)-5-ethylbarbituric acid

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5-(2-Cyclohexylideneethyl)-5-ethylbarbituric acid is a chemical compound belonging to the class of barbiturates. It is a synthetic derivative of barbituric acid and is characterized by its unique structure, which includes a cyclohexylidene group and an ethyl group attached to the 5th carbon of the barbituric acid core.

Chemical Structure[edit | edit source]

The chemical structure of 5-(2-Cyclohexylideneethyl)-5-ethylbarbituric acid is unique among barbiturates. The molecule consists of a six-membered pyrimidine ring, which is a key component of the barbituric acid core. Attached to the 5th carbon of this ring are two substituents: a cyclohexylideneethyl group and an ethyl group. The presence of these groups gives the molecule its name and distinguishes it from other barbiturates.

Synthesis[edit | edit source]

The synthesis of 5-(2-Cyclohexylideneethyl)-5-ethylbarbituric acid typically involves the reaction of barbituric acid with a suitable alkylating agent. The alkylating agent is chosen based on the desired substituents. In this case, a compound containing a cyclohexylideneethyl group and an ethyl group would be used.

Pharmacology[edit | edit source]

As a barbiturate, 5-(2-Cyclohexylideneethyl)-5-ethylbarbituric acid is expected to have sedative and hypnotic effects. However, the specific pharmacological properties of this compound have not been extensively studied. It is likely that the unique substituents on the 5th carbon of the molecule could influence its pharmacological activity.

Toxicology[edit | edit source]

Like other barbiturates, 5-(2-Cyclohexylideneethyl)-5-ethylbarbituric acid has the potential to be toxic if ingested in large amounts. Symptoms of barbiturate toxicity can include drowsiness, confusion, and respiratory depression. In severe cases, barbiturate overdose can be fatal.

See Also[edit | edit source]


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Contributors: Prab R. Tumpati, MD