5-AcO-DMT

From WikiMD's Food, Medicine & Wellness Encyclopedia

5-AcO-DMT (also known as O-Acetylpsilocin or Psilacetin) is a psychedelic drug used primarily for its hallucinogenic effects. It is a synthetic compound and is considered a prodrug to psilocin, one of the active components in psilocybin mushrooms.

Chemistry[edit | edit source]

5-AcO-DMT is a member of the tryptamine class of psychedelic compounds. It is an O-acetylated psilocin, hence its full chemical name is 3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl acetate. The compound is a white crystalline solid at room temperature.

Pharmacology[edit | edit source]

5-AcO-DMT is metabolized in the body to produce psilocin, which is responsible for its psychedelic effects. The exact mechanism of action is not fully understood, but it is believed to work by binding to and activating serotonin receptors in the brain, particularly the 5-HT2A receptor.

Effects[edit | edit source]

The effects of 5-AcO-DMT are similar to those of other psychedelic drugs. They can include visual and auditory hallucinations, altered perception of time and space, enhanced introspection, and emotional experiences. The intensity and duration of these effects can vary depending on the dose and individual's physiology.

Legal Status[edit | edit source]

The legal status of 5-AcO-DMT varies by country. In some countries, it is classified as a controlled substance, while in others it is legal to possess and use.

Safety[edit | edit source]

As with all psychedelic substances, the use of 5-AcO-DMT carries risks. These can include psychological distress, dangerous behavior due to altered perceptions, and potential negative interactions with other substances. It is recommended that individuals use this substance responsibly and under the guidance of a healthcare professional.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD