5-Iodowillardiine

5-Iodowillardiine is a synthetic compound that is used in scientific research. It is an agonist for the AMPA and kainate receptors, which are types of ionotropic glutamate receptors in the brain.

Chemistry

5-Iodowillardiine is a derivative of willardiine, a naturally occurring compound found in the seeds of the plant Acacia willardiana. The addition of an iodine atom at the 5 position of the molecule increases its potency as an agonist at the AMPA and kainate receptors.

Pharmacology

As an agonist for the AMPA and kainate receptors, 5-Iodowillardiine can stimulate these receptors to mimic the action of the neurotransmitter glutamate. This can be useful in research into the function of these receptors and the role they play in various neurological and psychiatric disorders.

Uses in Research

5-Iodowillardiine has been used in a variety of research contexts. For example, it has been used to study the effects of AMPA and kainate receptor activation in models of neurological disorders such as epilepsy and neurodegenerative diseases. It has also been used to investigate the role of these receptors in psychiatric disorders such as schizophrenia and depression.

Safety

As a research chemical, 5-Iodowillardiine is not intended for human consumption. Its safety profile in humans is unknown.

See Also

• AMPA receptor
• Kainate receptor
• Glutamate receptor
• Neurotransmitter
• Neurological disorders
• Psychiatric disorders

5-Iodowillardiine Resources
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