5F-PCN

5F-PCN is a synthetic cannabinoid that is used in scientific research and has been sold online as a designer drug. It is a potent agonist of the CB1 receptor and CB2 receptor with EC50 values of 0.21 nM and 0.29 nM, respectively. It is closely related to other synthetic cannabinoids like 5F-ADB, which is illegal in many countries.

Chemistry

5F-PCN is a synthetic cannabinoid that is structurally related to natural cannabinoids and other synthetic cannabinoids. It is classified as a naphthoylindole, which is a type of synthetic cannabinoid. The chemical name for 5F-PCN is N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(5-fluoropentyl)-1H-indole-3-carboxamide.

Pharmacology

5F-PCN acts as a potent agonist for the CB1 and CB2 receptors, with EC50 values of 0.21 nM and 0.29 nM, respectively. This makes it a full agonist of these receptors. The exact mechanism of action is not fully understood, but it is believed to involve the activation of these receptors, which leads to the psychoactive effects observed with this compound.

Effects

The effects of 5F-PCN are similar to those of other synthetic cannabinoids and include euphoria, relaxation, and changes in perception. However, the potency and toxicity of 5F-PCN are not well studied, and it has been associated with numerous adverse effects and fatalities.

Legal status

5F-PCN is illegal in many countries, including the United States, where it is classified as a Schedule I controlled substance. It is also illegal in many European countries, including the United Kingdom, where it is classified as a Class B drug.

See also

• Synthetic cannabinoids
• Cannabinoid receptor
• 5F-ADB

5F-PCN Resources
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