60S ribosomal protein L36a

Ideogram human chromosome X

60S Ribosomal Protein L36a

60S Ribosomal Protein L36a is a protein that in humans is encoded by the RPL36A gene. It is a component of the large 60S ribosomal subunit. This protein plays a crucial role in protein synthesis by aiding in the formation of the ribosome, the cellular machinery responsible for translating messenger RNA into proteins.

Structure

The 60S Ribosomal Protein L36a is a ribosomal protein that is part of the large 60S ribosomal subunit. It is composed of a specific sequence of amino acids that allows it to interact with other ribosomal proteins and RNA molecules to form the functional ribosome.

Function

As a component of the ribosome, 60S Ribosomal Protein L36a plays a vital role in the translation process. It helps in the accurate positioning of the ribosome on the messenger RNA and facilitates the binding of transfer RNA molecules carrying amino acids to the ribosome. This protein is essential for the proper assembly and function of the ribosome during protein synthesis.

Clinical Significance

Mutations in the RPL36A gene encoding 60S Ribosomal Protein L36a have been associated with certain genetic disorders and diseases. Dysregulation of ribosomal proteins like L36a can lead to defects in protein synthesis, which may contribute to various pathological conditions.