7-OH-DPAT

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7-OH-DPAT is a compound used in scientific research, specifically in the study of the dopamine receptor. It is a potent agonist at the D2 dopamine receptor and the D3 dopamine receptor. The compound is used in research to understand the function and role of these receptors in the brain.

Chemistry[edit | edit source]

7-OH-DPAT is a synthetic compound, meaning it is not naturally occurring. It is a derivative of the naturally occurring compound dopamine, which is a key neurotransmitter in the brain. The compound is named for its structure, which includes a 7-hydroxy group (OH) and a dipropylamino tetralin (DPAT) group.

Pharmacology[edit | edit source]

As an agonist at the D2 and D3 dopamine receptors, 7-OH-DPAT has the ability to activate these receptors. This can have a variety of effects, depending on the specific location and function of the receptors in the brain. For example, activation of D2 receptors can have effects on motor control, while activation of D3 receptors can have effects on mood and behavior.

Research Use[edit | edit source]

7-OH-DPAT is used in research to study the function and role of the D2 and D3 dopamine receptors. By using this compound to selectively activate these receptors, researchers can gain insight into their function and role in the brain. This can help to improve our understanding of a variety of neurological and psychiatric conditions, including Parkinson's disease, schizophrenia, and depression.

See Also[edit | edit source]

7-OH-DPAT Resources
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Contributors: Prab R. Tumpati, MD