8-OH-DPAT

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8-OH-DPAT (8-Hydroxy-2-(di-n-propylamino)tetralin) is a research chemical of the aminotetralin chemical class which was developed in the 1980s and has been widely used in scientific research. It is a serotonin agonist with selectivity for the 5-HT1A receptor subtype.

Chemistry[edit | edit source]

8-OH-DPAT is a member of the aminotetralin chemical class. It is structurally related to compounds such as 8-OH-DPAT, which are known to act as potent and selective agonists for the 5-HT1A receptor.

Pharmacology[edit | edit source]

8-OH-DPAT acts as a potent and selective agonist for the 5-HT1A receptor, and this is thought to be responsible for its psychoactive effects. It has been used in scientific research to provoke 5-HT1A receptor responses.

Uses[edit | edit source]

8-OH-DPAT is used primarily in scientific research. It has been used to study the role of 5-HT1A receptors in various processes including anxiety, depression, schizophrenia, and neurogenesis.

Side Effects[edit | edit source]

As a research chemical, 8-OH-DPAT is not intended for human consumption, and its side effects have not been thoroughly studied. However, due to its action as a 5-HT1A receptor agonist, it may potentially cause side effects similar to other drugs with this mechanism of action, such as nausea, dizziness, and sedation.

See Also[edit | edit source]

8-OH-DPAT Resources
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Contributors: Prab R. Tumpati, MD