8,11-Dihydroxy-THC

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8,11-Dihydroxy-THC is a cannabinoid derivative of THC, the principal psychoactive constituent of cannabis. As a hydroxylated form of THC, 8,11-Dihydroxy-THC exhibits unique properties and effects compared to its parent compound.

Chemistry[edit | edit source]

8,11-Dihydroxy-THC is characterized by the presence of two hydroxyl groups added to the THC molecule. The specific positions of these groups on the 8th and 11th carbons significantly alter the molecule's pharmacological activity. The chemical modifications impact the solubility, binding affinity, and overall metabolic stability of the compound.

Pharmacology[edit | edit source]

The pharmacological effects of 8,11-Dihydroxy-THC are believed to be mediated through its interaction with the cannabinoid receptors CB1 and CB2, similar to other cannabinoids. However, the presence of additional hydroxyl groups may enhance its affinity or alter its efficacy at these receptor sites. The exact pharmacological profile remains under investigation.

Medical Research[edit | edit source]

Research into 8,11-Dihydroxy-THC is ongoing, with studies aimed at understanding its potential therapeutic benefits. It is speculated that, like other cannabinoids, it may possess anti-inflammatory, analgesic, and neuroprotective properties. However, comprehensive clinical trials are necessary to substantiate these claims and to fully understand the therapeutic potential and safety profile of 8,11-Dihydroxy-THC.

Legal Status[edit | edit source]

The legal status of 8,11-Dihydroxy-THC varies by jurisdiction, often reflecting the regulations applicable to THC and related cannabinoids. In many regions, compounds derived from cannabis, including various THC derivatives, are controlled substances.

See Also[edit | edit source]


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Contributors: Prab R. Tumpati, MD