ACAD10

ACAD10 is a gene that encodes the protein Acyl-CoA Dehydrogenase Family Member 10 in humans. This protein is a member of the acyl-CoA dehydrogenase family of enzymes, which catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids.

Function

The ACAD10 gene is involved in the fatty acid metabolism process, specifically in the oxidation of long-chain fatty acids. The protein encoded by this gene is an enzyme that catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. This enzyme is crucial for energy production, as it helps break down fats into smaller molecules that can be used for energy.

Clinical Significance

Mutations in the ACAD10 gene have been associated with various medical conditions. For instance, they have been linked to non-insulin-dependent diabetes mellitus (NIDDM), a condition characterized by high blood sugar levels caused by the body's inability to properly use insulin.

Research

Research into the ACAD10 gene and its associated protein is ongoing. Scientists are particularly interested in understanding how mutations in this gene may contribute to the development of metabolic disorders, such as diabetes and obesity.

See Also

• Acyl-CoA dehydrogenase
• Fatty acid metabolism
• Non-insulin-dependent diabetes mellitus